September 20, 2015

The controversial science behind "immortality"

In the SXSW accepted film "The Immortalists" two eccentric scientists struggle to create eternal youth in a world they call “blind to the tragedy of old age.” As they battle their own aging and suffer the loss of loved ones, their scientific quest ultimately becomes personal.

I am hoping that the documentary focuses on more than just telomerase and instead takes a look at a more complete picture such as described by the SENS (Strategies for Engineered Negligible Senescence) approach cause otherwise I am afraid it will prove to be a quite dumbed down and simplistic vision.

By the looks of it The Immortalists should provide a balanced view as the cast is about evenly divided between those who think that fighting aging is a good idea and those who say it isn't feasible or that we shouldn't bother.

Those last few shots of de Grey and his missus... It's always refreshing to see someone own what lesser beings might wrongly choose to hide in shame. Good stuff! :) It's obvious that this documentary will try to infuse the rather depressing topic of death with a dose of lighthearted humor.

Aubrey de Grey is probably one of the most famous biogerontologists alive and has been trying to get the fight against aging on the agenda for a long time. Before he co-founded SENS he was one of the main drivers behind the creation of the Methuselah foundation, named after both the biblical figure who supposedly ;) lived to be 969 years and the very real 4845 year-old Great Basin bristlecone pine which is still alive and kicking today somewhere in the White Mountains regio of eastern California. He was the main instigator behind the Mprize (Methuselah Mouse Prize) which has awarded various teams for achieving preset life extension and rejuvenation milestones in mice. Check out this TED talk from 7 years ago if you want a small primer on his work.

Alternatively you can check out this hour long lecture for a more detailed look at why he thinks that SENS will help us conquer aging - Aubrey de Grey, "Ending Aging" | Talks at Google

If you really want to start digging into the science behind aging you might want to take a look at the SENS foundation's site and their archive of lectures. The SENS conferences regularly attract huge names who run some of the biggest labs in the world. For example, last year's keynote, SENS6, was opened by George Church and SENS5 was opened by Caleb Finch. - http://www.sens.org/videos

And finally, if you are looking for a spicy debate, just last week he was featured on the BBC show HARDtalk where he had to defend his views from one of journalism's bulldogs; Stephen Sackur.

http://en.wikipedia.org/wiki/Methuselah
http://en.wikipedia.org/wiki/Methuselah_(tree)
http://en.wikipedia.org/wiki/Gerontology
http://en.wikipedia.org/wiki/Biomedical_gerontology
http://en.wikipedia.org/wiki/Telomerase
http://en.wikipedia.org/wiki/Strategies_for_Engineered_Negligible_Senescence

Abiogenesis a.k.a Alex Ries

I've decided to start a series on my favorite artists so from now on you can expect from me about a post a week featuring the works of one particularly creative genius. Painters, sculptors, musicians, writers, directors, engineers, architects, coders, ... artists of all stripes and colors will get a turn in the spotlight.

I am kicking things off with someone who many consider to be a god as he wields the power to pull never before seen fully living and breathing worlds into being. Perhaps the foremost SF artist of our times, he doesn't create pictures, he creates scenes so real they radiate history.

Alex Ries is a Melbourne based illustrator and concept artist with several years’ experience across the industry. His artworks have been featured by publishers including Cosmos Magazine, Pearson Education Canada, and the Discovery Channel.

Receiving his education at the University of Melbourne, Alex graduated with a Bachelor of Creative Arts. Studies in diverse visual media including painting, 3D visualisation and film provided a broad creative skills base from which to operate.

This education and experience, coupled with a strong interest in biology, zoology and real-world technology, has fostered an artistic style able to not only accurately illustrate life from the real world, but fictional life as well.

Rumor has it that he's been hard at work on a book that will detail the complete history of life on another world. From the planet's formation to the evolutionary origins of many of its species to ultimately the development of a culture that like us has managed to soar into space. Can't wait! :)



http://www.alexries.com/
http://abiogenisis.deviantart.com/
http://en.wikipedia.org/wiki/Abiogenesis

April 11, 2015

Construction of the ESS, the European Spallation Source, has begun!

The town of Lund, in Sweden, is already home to a number of major scientific facilities, including one of the most advanced synchrotron X-ray sources, the MAX IV, scheduled for inauguration in 2016. Now Lund will also be the site of the world's most powerful neutron source, the €1.8 billion European Spallation Source (ESS).

Spallation is the process for producing neutrons by means of a particle accelerator and a heavy metal target. The ESS's 600-meter long linear accelerator will fire protons derived from hydrogen gas at a velocity just below the speed of light at a target made out of the metal tungsten.

The metal target absorbs the proton beam and transforms into fast neutrons. Which is basically just a really polite way of saying that the proton beam rips the target a new one which causes it to spill its guts all over the place, showering its environment with fast neutrons. To contain the extreme level of highly penetrating gamma and fast neutron radiation the target chamber is surrounded by a radiation shielding system, a 7000 ton sphere of steel. If that kind of talk doesn't get your heart racing I don't know what will! ;)

When the neutrons are slowed down they are, guided by beam lines, lead towards experimental stations where they allow us to see through matter on the smallest of scales. Because neutrons have no charge, they don't scatter on electrons and can penetrate deep into atoms and probe atomic nuclei directly, which is not possible with X-rays.

Two factors make neutrons especially interesting. With X-rays you only "see" the heavy elements, but with neutrons, which interact with light elements such as hydrogen and carbon, you can probe a wider range of materials, with applications in molecular biology, biomedical research, and even food science.

The second factor is that neutrons carry a magnetic moment. They interact with the magnetic moments of atoms and thus can assist researchers investigating materials like superconductors.

A big thanks to the more than a dozen European countries that are funding the project, especially Sweden and Denmark, the two biggest backers. If all goes well first light should be produced in 2019.

http://europeanspallationsource.se/science-using-neutrons

http://en.wikipedia.org/wiki/European_Spallation_Source

Jean-Léon Gérôme - torn between romantic idealism and historic realism

Jean-Léon Gérôme, born 1824 in France, was a master of the style now known as Academicism. His many paintings depicting historical scenes, Greek mythology, Orientalism, portraits and other subjects guarantee his name will live on for centuries to come. That being said, he's also responsible for more than a few stunning sculptural works.

Gérôme’s artistic career began in 1840 in Paris where he practiced his craft under Paul Delaroche's watchful eye. He accompanied Delaroche to Italy to continue his studies. Two years later he returned to Paris and attended the École des Beaux-Arts, entering the Prix de Rome competition in hopes of returning to Italy, but he failed to qualify for the final stage in 1846 because of his inadequate figure drawing. Consequently, Gérôme became obsessed with painting the perfect nude—an ambition he would harbor throughout his life.

In 1853, Gérôme moved to the Boîte à Thé, a group of studios in the Rue Notre-Dame-des-Champs, Paris. This would become a meeting place for other artists, writers and actors. George Sand entertained in the small theater of the studio the great artists of her time such as the composers Berlioz, Brahms and Rossini and the novelists Gautier and Turgenev. No doubt this was an environment conductive to the cross pollination of artistic ideas. Gérôme both inspired and was influenced by these greats.

He made his name rendering allegorical scenes from ancient Greece and Rome in exquisite detail, often incorporating neoclassical concepts. His breakthrough in France allowed him to travel the world and his many journeys proved to be a great inspiration, birthing a great deal of historical paintings. His visits to Northern Africa, Egypt in particular, made a lasting impression and he would return to it in his paintings ever after.

Although Gérôme is famous for his idealized depictions of reality, he achieved detail so vivid that his work, even though the scenes and people in them were larger than life, appeared to ring true. He perfected many of the techniques that realists would later employ and in many ways is responsible for the realist movement's birth as it took off in response to the exaggerated reality he had helped popularize. In 1902 he said; "Thanks to photography, Truth has at last left her well.". I for one am glad that Gérôme was born ahead of what might have been his time. He blurred the lines between the real and the fantastic most beautifully.

Jean-Léon Gérôme died in his atelier on 10 January 1904. He was found in front of a portrait of Rembrandt and close to his own painting "The Truth".

Juice Rap News - History is Happening

Giordano Nanni and Hugo Farrant have been broadcasting their satirical news show from a suburban backyard home-studio in Melbourne, Australia for quite a while now. Given how awesome their productions are it amazes me that they still aren't household names! I've shared some of their shows before but their latest creation just might be one of their best yet. ;)

"Today we travel into the pure world of sci-fi to investigate the much vaunted, mysterious potential future event known as 'The Singularity'. What will a machine consciousness mean for humanity? What are the ethical, political, military and philosophical implications of strong A.I.? And what would an AI sound like when spitting rhymes over a dope beat? All this and more shall be revealed in Rap News 28."

Net Neutrality [RAP NEWS 25]
The Energy Crisis - feat. Copernicus [RAP NEWS 22]
Big Brother is WWWatching You - feat. George Orwell [RAP NEWS 15]
"THE NEWS" - feat Sage Francis [RAP NEWS 21]

Hieronymus Bosch - Master of the monstrous

Around 1450 Hieronymus Bosch, born Jheronimus van Aken, was squeezed into being in the Duchy of Brabant, a state of the Holy Roman Empire, at the time part of the Burgundian Netherlands and near the end of his life part of the Habsburg Netherlands. Little is known of Bosch’s life or training. He left behind no letters or diaries. Neither is anything known of his personality or his thoughts on the meaning of his art.

What we do know is that in 1463, 4000 houses in his town of 's-Hertogenbosch were destroyed by a catastrophic fire, which the then approximately 13-year-old Bosch presumably witnessed. Perhaps this event provided the foundation for some of the hellish scenes he came up with? We can only guess.

Fewer than 25 paintings remain today that can be attributed to him. In the late sixteenth-century, Philip II of Spain acquired many of Bosch's paintings, including some probably commissioned and collected by Spaniards active in Bosch's hometown; as a result, the Prado Museum in Madrid now owns most of his best work including; The Adoration of the Magi, The Garden of Earthly Delights, the tabletop painting of The Seven Deadly Sins and the Four Last Things, the The Haywain Triptych and The Stone Operation.

His Garden of Earthly Delights is probably one of the most famous paintings ever created and it's easy to see why. 500 years after Bosch introduced it to the world, the explosively colored fantastical scene it depicts is no less remarkable. It grabs attention instantly and effortlessly holds it for within its frame there is so much going on that the harder you look, the more details you uncover.

Art historians and critics frequently interpret his painting as a didactic warning on the perils of life's temptations. However, the intricacy of its symbolism, particularly that of the central panel, has led to a wide range of scholarly interpretations over the centuries. Twentieth-century art historians are divided as to whether the triptych's central panel is a moral warning or a panorama of paradise lost.

http://en.wikipedia.org/wiki/The_Garden_of_Earthly_Delights
http://en.wikipedia.org/wiki/The_Haywain_Triptych
http://en.wikipedia.org/wiki/The_Hermit_Saints
http://en.wikipedia.org/wiki/Triptych_of_the_Temptation_of_St._Anthony
http://en.wikipedia.org/wiki/The_Last_Judgment_(Bosch_triptych,_Bruges)

Amazing how deeply you can miss a place you've never been

"The quality of a civilization is measured not by what it has to do, but by what it wants to do." -Bruce Murray